Research


 

Here is a selection of links and research articles on ketamine and lidocaine for depression, PTSD, pain, and other conditions. The articles here represent a portion of the information available, and are meant to supplement your own research and discussions with your referring physician.

STUDIES

 

The Effect of Ketamine Infusion Treatment Schedule on Depression Severity

  • Brittany O'Brien
  • Allison Wells
  • Marijin Lijffijt
  • Michelle Davis
  • Jesse Wells
  • Alan C. Swann
  • Sanjay J. Mathew
Baylor College of Medicine Lone Star Infusion, PPLC Michael E. DeBakey Veterans Affairs Medical Center
 

Does Childhood Trauma Impact Outcomes in Adults Receiving Ketamine for Depression?

  • Brittany O'Brien
  • Allison Wells
  • Marijin Lijffijt
  • Michelle Davis
  • Jesse Wells
  • Alan C. Swann
  • Sanjay J. Mathew
Baylor College of Medicine Lone Star Infusion, PPLC Michael E. DeBakey Veterans Affairs Medical Center
 

The Impact of Childhood Maltreatment on Intravenous Ketamine Outcomes for Adult Patients with Treatment-Resistant Depression

  • Brittany O'Brien
  • Marijin Lijffijt
  • Allison Wells
  • Alan C. Swann
  • Sanjay J. Mathew
Pharmaceuticals Multidisciplinary Digital Publishing Institute

Medical Literature

 

Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression

  • Marije aan het Rot
  • Katherine A. Collins
  • James W. Murrough
  • Andrew M. Perez
  • David L. Reich
  • Dennis S. Charney
  • Sanjay J. Mathew
Biological Psychiatry
 

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

  • Anita E. Autry
  • Megumi Adachi
  • Elena Nosyreva
  • Elisa S. Na
  • Maarten F. Los
  • Peng-fei Cheng
  • Ege T. Kavalali
  • Lisa M. Monteggia
Nature Journal
 

A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression

  • Nancy Diazgranados
  • Lobna Ibrahim
  • Nancy E. Brutsche
  • Andrew Newberg
  • Phillip Kronstein
  • Sami Khalife
  • William A. Kammerer
  • et al
Archives of General Psychiatry
 

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

  • Ronald S. Duman
  • George K. Aghajanian
Science Journal
 

Signaling Pathways Underlying the Rapid Antidepressant Actions of Ketamine

  • Ronald S. Duman
  • Nanxin Li
  • Rong-Jian Liu
  • Vanja Duric
  • George K. Aghajanian
Neuropharmacology Journal
 

Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder: A Randomized Clinical Trial

  • Adriana Feder
  • Michael K. Parides
  • James W. Murrough
  • Andrew M. Perez
  • Julia E. Morgan
  • Shireen Saxena
  • Katherine Kirkwood
  • et al
Archives of General Psychiatry
 

Multi-Day Low Dose Ketamine Infusion for the Treatment of Complex Regional Pain Syndrome

  • Michael E. Goldberg
  • Richard Domsky
  • Denise Scaringe
  • Robert Hirsh
  • Jessie Dotson
  • Imran Sharaf
  • Marc C. Torjman
  • Robert J. Schwartzman
Pain Physicians Journal
 

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

  • Nanxin Li
  • Rong-Jian Liu
  • Jason M. Dwyer
  • Xiao-Yuan Li
  • George Aghajanian
  • Ronald S. Duman
  • et al
Biological Psychiatry
 

Maintenance Ketamine Treatment Produces Long-term Recovery from Depression

  • Michael M. Messer
  • Irina V. Haller

Primary Psychiatry

 

Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression: A Two-Site Randomized Controlled Trial

  • James W. Murrough
  • Dan V. Iosifescu
  • Lee C. Chang
  • Rayan K. Al Jurdi
  • Charles E. Green
  • Andrew M. Perez
  • et al
The American Journal of Psychiatry
 

Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression

  • James W. Murrough
  • Andrew M. Perez
  • Sarah Pillemer
  • Jessica Stern
  • Michael K. Parides
  • Marije aan het Rot
  • et al
Society of Biological Psychiatry
 

Efficacy and adverse effects of intravenous lignocaine therapy in fibromyalgia syndrome

  • Raphael JH
  • Southall JL
  • Treharne GJ
  • Kitas GD
BMC Musculoeskeletal Disorders
 

Intravenous Therapies in the Management of Neuropathic Pain: A Review on the Use of Ketamine and Lidocaine in Chronic Pain Management

  • Harsha Shanthanna
InTech Open
 

Differential Efficacy of Ketamine in the Acute versus Chronic Stages of Complex Regional Pain Syndrome in Mice

  • Maral Tajerian
  • David Leu
  • Phillip Yang
  • Ting Ting Huang
  • Wade S. Kingery
  • J. David Clark
Anesthesiology Journal
 

A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression

  • Carlos A. Zarate
  • Jaskaran B. Singh
  • Paul J. Carlson
  • Nancy E. Brutsche
  • Rezvan Ameli
  • et al
Archives of General Psychiatry
 

The Impact of Childhood Maltreatment on Intravenous Ketamine Outcomes in Adult Patients with TreatmentResistant Depression

  • Brittany O'Brien
  • Marijn Lijffijt
  • Allison Wells
  • Alan C Swann
  • Sanjay J Mathew
Pharmaceuticals

Services

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OCD

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Depression

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PTSD

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Anxiety

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Bipolar Disorder

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Neuralgia

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CRPS/RSD

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Other Symptoms

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