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CRPS/RSD

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Ketamine Infusions for Complex Regional Pain Syndrome (CRPS/RSD)

Living with chronic pain conditions such as Complex Regional Pain Syndrome (CRPS), formerly called Reflex Sympathetic Dystrophy (RSD), can make everyday activities difficult and impact your career, relationships, and overall quality of life.


At Lone Star Infusion in Houston, Texas, our experienced team offers ketamine IV infusion therapy to help reduce pain, improve neural function, and manage other related symptoms.

Options

Treatment Options for CRPS/RSD

  • 1
    One-Hour High Dose Infusion
    • Designed for individuals with mild CRPS or neuropathic pain.
    • Provides rapid pain relief and symptom reduction in a shorter session.
    • Often used as a starting point to assess patient response and tolerance to ketamine therapy.
  • 2
    Four-Hour High Dose Infusion
    • Recommended for individuals with severe CRPS/RSD or complex neuropathic pain.
    • Offers more intensive treatment to address stronger or widespread symptoms.
    • Typically provides longer-lasting relief due to the extended infusion duration and higher cumulative dose.
Infusion Comparison Table
Infusion Treatment Comparison
Feature One-Hour High Dose Infusion Four-Hour High Dose Infusion
Target Patients Mild CRPS or neuropathic pain Severe CRPS/RSD or complex neuropathic pain
Duration 1 hour 4 hours
Purpose Rapid relief and symptom reduction; initial assessment of response Intensive treatment for stronger or widespread symptoms
Cumulative Dose Lower Higher
Expected Relief Shorter-term relief; may require follow-up sessions Longer-lasting relief due to higher dose and extended infusion
Recommended Use Starting point for new patients or milder symptoms For patients needing more intensive pain management

Ketamine and CRPS/RSD

01

What is CRPS/RSD?

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Complex Regional Pain Syndrome (CRPS), also known as Reflex Sympathetic Dystrophy (RSD), is a condition affecting the autonomic and sympathetic nervous systems. It causes constant, intense, and severe pain that is often disproportionate to the original injury.

In addition to pain, CRPS/RSD may cause:

  • Swelling
  • Muscle spasms
  • Changes to your skin color and texture
  • Extreme sensitivity to touch and temperature
  • Insomnia
  • Problems with concentration and memory
  • Disability

There are two types of CRPS :

  • Type I : Occurs after a minor or secondary nerve injury from events such as soft tissue injuries, bone fractures, heart problems, or repetitive strain injuries (e.g., carpal tunnel syndrome).
  • Type II : Involves a definable major nerve injury and requires prompt treatment to avoid chronic pain and debilitation.
02

How is CRPS/RSD treated?

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At Lone Star Infusion, our Anesthesiologist/Anesthetist team uses ketamine IV infusion therapy to treat chronic pain conditions. Ketamine works with your neurons to improve neural function and reduce neurological pain.

Many patients achieve long-term relief with a combination of an initial infusion series followed by regular booster treatments

03

What Happens During Ketamine IV Therapy for CRPS/RSD?

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Before beginning treatment, you will have a comprehensive consultation with an Anesthesiologist/Anesthetist to determine if ketamine therapy is appropriate.

  • Infusion duration and frequency: Patients often receive one-hour high-dose infusions on an as-needed basis. A common regimen may include one or two treatments every six to eight weeks to manage symptoms. Some patients maintain results with one-hour infusions every eight weeks, typically after several years of therapy.
  • Monitoring and safety: You will be continuously monitored during infusions to ensure safety and effectiveness. Best-practice standards and protocols are followed for every session.
04

How many infusions will I need?

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A series of infusions, followed by maintenance treatments, provides the most effective and lasting relief, with each infusion building on the previous session.

  • For psychiatric symptoms, we often start with a series of six infusions over several weeks, followed by maintenance treatments every 3–5 weeks as needed.
  • For chronic pain conditions, treatment may involve one or more one-hour high-dose infusions, followed by one or two infusions every six to eight weeks for symptom management.

The number and frequency of treatments vary depending on individual needs, symptom severity, and response to therapy. Over time, we work with patients to extend the interval between treatments when possible.

We are Here for You

Take the Next Step

If you want to learn more about how ketamine IV infusion therapy can help manage CRPS/RSD and other chronic pain conditions, call Lone Star Infusion or schedule an appointment online today.

Important Notice Regarding Discontinuation of Ketamine Treatment Services

Lone Star Infusion will discontinue providing ketamine infusion and treatment services effective February 23, 2026. This decision was not made lightly, and we understand this news may be concerning to you.

What This Means for Your Care

After February 23, 2026 our clinic will no longer provide ketamine treatments. You will need to establish care with another provider to continue ketamine therapy, or work with your treating psychiatrist or pain management physician to explore alternative treatment options.

Your Immediate Next Steps

  1. Contact your prescribing psychiatrist, primary care physician, or pain management specialist to discuss your ongoing treatment plan and alternatives.
  2. If you wish to continue ketamine therapy, please review the enclosed list of physician-supervised ketamine clinics in the Houston area. We do not endorse any particular provider; this list is provided for your convenience only.
  3. Contact our office to schedule any final appointments before [closure date] and to discuss your transition of care.

Your Medical Records

Your treatment records will remain available through Lone Star Infusion. To request copies of your records or to authorize transfer to a new provider, please contact our office at 281.947.3268 or send a written request to 14740 Barryknoll Lane, Ste. 140, Houston, TX 77079. There is no charge for transferring records to your new treatment provider.

Continuation of Care During Transition

We stay committed to your care during this transition period. Please contact our office at 281.947.3268 if you have questions, need to schedule appointments before our closure date, or require assistance with your transition to a new provider.

We understand this transition may be difficult, and we appreciate the trust you have placed in us for your care. Our staff is available to assist you during this process.

Sincerely,
Chauncey Jones, M.D.
Lone Star Infusion